He has appeared around several film, including a leading human role ''My Best Friend's Wedding across from Cameron Diaz and Julia Roberts.

He is married to actress Catherine Keener, and a father of Clyde Mulroney. His father occurs as law prof at Villanova University School of Law.

He is typically confused for actor Dylan McDermott.

Selected filmography
The Family Stone (2005) Must Love Dogs (2005) The Wedding Date (2005) About Schmidt (2002) Trixie (2000) My Best Friend's Wedding (1997) Bastard Out of Carolina (1996) How to Make an American Quilt (1995) Bad Girls (1994) Silent Tongue (1994) Point of No Return (1993) Where the Day Takes You (1992) Samantha (1992) Longtime Companion (1990) Young Guns'' (1988)